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PARP1 Is a TRF2-associated Poly(ADP-Ribose)Polymerase and Protects Eroded Telomeres

Poly(ADP-ribose)polymerase 1 (PARP1) is well characterized for its role in base excision repair (BER), where it is activated by and binds to DNA breaks and catalyzes the poly(ADP-ribosyl)ation of several substrates involved in DNA damage repair. Here we demonstrate that PARP1 associates with telomer...

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Detaylı Bibliyografya
Asıl Yazarlar: Gomez, Marla, Wu, Jun, Schreiber, Valérie, Dunlap, John, Dantzer, Françoise, Wang, Yisong, Liu, Yie
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The American Society for Cell Biology 2006
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1415310/
https://ncbi.nlm.nih.gov/pubmed/16436506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E05-07-0672
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