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Release of Interleukin-1α or Interleukin-1β Depends on Mechanism of Cell Death

The cytokine interleukin-1 (IL-1) has two main pro-inflammatory forms, IL-1α and IL-1β, which are central to host responses to infection and to damaging sterile inflammation. Processing of IL-1 precursor proteins to active cytokines commonly occurs through activation of proteases, notably caspases a...

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Detalhes bibliográficos
Main Authors: England, Hazel, Summersgill, Holly R., Edye, Michelle E., Rothwell, Nancy J., Brough, David
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4047367/
https://ncbi.nlm.nih.gov/pubmed/24790078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.557561
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