Retinoschisin gene therapy in photoreceptors, Müller glia, or all retinal cells in the Rs1h−/− mouse

X-linked retinoschisis, a disease characterized by splitting of the retina, is caused by mutations in the retinoschisin gene, which encodes a secreted cell adhesion protein. Currently, there is no effective treatment for retinoschisis, though viral vector-mediated gene replacement therapies offer pr...

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Detaylı Bibliyografya
Asıl Yazarlar: Byrne, Leah C., Öztürk, Bilge E., Lee, Trevor, Fortuny, Cécile, Visel, Meike, Dalkara, Deniz, Schaffer, David V., Flannery, John G.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4047144/
https://ncbi.nlm.nih.gov/pubmed/24694538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2014.31
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