AAV-Mediated, Optogenetic Ablation of Müller Glia Leads to Structural and Functional Changes in the Mouse Retina

Müller glia, the primary glial cell in the retina, provide structural and metabolic support for neurons and are essential for retinal integrity. Müller cells are closely involved in many retinal degenerative diseases, including macular telangiectasia type 2, in which impairment of central vision may...

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Main Authors: Byrne, Leah C., Khalid, Fakhra, Lee, Trevor, Zin, Emilia A., Greenberg, Kenneth P., Visel, Meike, Schaffer, David V., Flannery, John G.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3785414/
https://ncbi.nlm.nih.gov/pubmed/24086689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0076075
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