Identification of Divergent Protein Domains by Combining HMM-HMM Comparisons and Co-Occurrence Detection

Identification of protein domains is a key step for understanding protein function. Hidden Markov Models (HMMs) have proved to be a powerful tool for this task. The Pfam database notably provides a large collection of HMMs which are widely used for the annotation of proteins in sequenced organisms....

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Main Authors: Ghouila, Amel, Florent, Isabelle, Guerfali, Fatma Zahra, Terrapon, Nicolas, Laouini, Dhafer, Yahia, Sadok Ben, Gascuel, Olivier, Bréhélin, Laurent
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2014
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4046975/
https://ncbi.nlm.nih.gov/pubmed/24901648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0095275
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