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Identification of Divergent Protein Domains by Combining HMM-HMM Comparisons and Co-Occurrence Detection
Identification of protein domains is a key step for understanding protein function. Hidden Markov Models (HMMs) have proved to be a powerful tool for this task. The Pfam database notably provides a large collection of HMMs which are widely used for the annotation of proteins in sequenced organisms....
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4046975/ https://ncbi.nlm.nih.gov/pubmed/24901648 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0095275 |
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