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Improving pairwise comparison of protein sequences with domain co-occurrence

Comparing and aligning protein sequences is an essential task in bioinformatics. More specifically, local alignment tools like BLAST are widely used for identifying conserved protein sub-sequences, which likely correspond to protein domains or functional motifs. However, to limit the number of false...

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Veröffentlicht in:PLoS Comput Biol
Hauptverfasser: Menichelli, Christophe, Gascuel, Olivier, Bréhélin, Laurent
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5766236/
https://ncbi.nlm.nih.gov/pubmed/29293498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005889
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