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Genetic Background Drives Transcriptional Variation in Human Induced Pluripotent Stem Cells
Human iPS cells have been generated using a diverse range of tissues from a variety of donors using different reprogramming vectors. However, these cell lines are heterogeneous, which presents a limitation for their use in disease modeling and personalized medicine. To explore the basis of this hete...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4046971/ https://ncbi.nlm.nih.gov/pubmed/24901476 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004432 |
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