PI3K-AKT signaling is a downstream effector of retinoid prevention of murine basal cell carcinogenesis

Basal cell carcinoma (BCC) is the most common human cancer. We have demonstrated previously that topical application of the retinoid prodrug tazarotene profoundly inhibits murine BCC carcinogenesis via RARγ-mediated regulation of tumor cell transcription. Since topical retinoids can cause adverse cu...

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Huvudupphovsmän: So, Po-Lin, Wang, Grace Y., Wang, Kevin, Chuang, Mindy, Calinisan Chiueh, Venice, Kenny, Paraic A., Epstein, Ervin H.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4046911/
https://ncbi.nlm.nih.gov/pubmed/24449057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-13-0304
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