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Pharmacologic retinoid signaling and physiologic retinoic acid receptor signaling inhibit basal cell carcinoma tumorigenesis

Basal cell carcinoma (BCC) is the most common human cancer. Patients with basal cell nevus syndrome (Gorlin syndrome) are highly susceptible to developing many BCCs as a result of a constitutive inactivating mutation in one allele of PATCHED 1, which encodes a tumor suppressor that is a major inhibi...

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Библиографические подробности
Опубликовано в: :Mol Cancer Ther
Главные авторы: So, Po-Lin, Fujimoto, Michele A., Epstein, Ervin H.
Формат: Artigo
Язык:Inglês
Опубликовано: 2008
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4457328/
https://ncbi.nlm.nih.gov/pubmed/18483315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-07-2043
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