Vitamin D3 Inhibits Hedgehog Signaling and Proliferation in Murine Basal Cell Carcinomas

Constitutive Hedgehog (HH) signaling underlies several human tumors, including basal cell carcinoma (BCC). Recently, Bijlsma et al (Bijlsma MF, et al. (2006) PLoS Biol 4: 1397–1410) reported a new biologic function for vitamin D3 in suppressing HH signaling in an in vitro model system. Based on that...

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Main Authors: Tang, Jean Y., Xiao, Tony Zheng, Oda, Yuko, Chang, Kris S., Shpall, Elana, Wu, Angela, So, Po-Lin, Hebert, Jennifer, Bikle, Daniel, Epstein, Ervin H.
Format: Artigo
Jezik:Inglês
Izdano: 2011
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3088781/
https://ncbi.nlm.nih.gov/pubmed/21436386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-10-0285
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