Vitamin D3 Inhibits Hedgehog Signaling and Proliferation in Murine Basal Cell Carcinomas

Constitutive Hedgehog (HH) signaling underlies several human tumors, including basal cell carcinoma (BCC). Recently, Bijlsma et al (Bijlsma MF, et al. (2006) PLoS Biol 4: 1397–1410) reported a new biologic function for vitamin D3 in suppressing HH signaling in an in vitro model system. Based on that...

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Hauptverfasser: Tang, Jean Y., Xiao, Tony Zheng, Oda, Yuko, Chang, Kris S., Shpall, Elana, Wu, Angela, So, Po-Lin, Hebert, Jennifer, Bikle, Daniel, Epstein, Ervin H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3088781/
https://ncbi.nlm.nih.gov/pubmed/21436386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-10-0285
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