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PI3K-AKT signaling is a downstream effector of retinoid prevention of murine basal cell carcinogenesis
Basal cell carcinoma (BCC) is the most common human cancer. We have demonstrated previously that topical application of the retinoid prodrug tazarotene profoundly inhibits murine BCC carcinogenesis via RARγ-mediated regulation of tumor cell transcription. Since topical retinoids can cause adverse cu...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4046911/ https://ncbi.nlm.nih.gov/pubmed/24449057 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-13-0304 |
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