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Genomic Dark Matter Sheds Light on EVI1-driven Leukemia

The orchestration of transcriptional programs depends on proper gene-enhancer pairing. While much remains to be learned about this process in normal development, two recent studies in Cell and Cancer Cell highlight how the genomic rearrangement of an enhancer plays a causal role in the onset of a le...

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Bibliographic Details
Main Authors: Koche, Richard, Armstrong, Scott A.
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4046890/
https://ncbi.nlm.nih.gov/pubmed/24735919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2014.03.031
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