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Accumulation of CTCF-binding sites drives expression divergence between tandemly duplicated genes in humans

BACKGROUND: During eukaryotic genome evolution, tandem gene duplication is the most frequent event giving rise to clustered gene families. However, how expression divergence between tandemly duplicated genes has emerged and maintained remain unclear. In particular, it is unknown if epigenetic regula...

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Detalhes bibliográficos
Main Authors: Liao, Ben-Yang, Chang, Andrew Ying-Fei
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4046690/
https://ncbi.nlm.nih.gov/pubmed/24564680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-S1-S8
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