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Neutral sphingomyelinase 2 deficiency is associated with lung anomalies similar to emphysema
Neutral sphingomyelinase 2 (nSMase2) upregulation was recently demonstrated to serve as a molecular link between smoke inhalation and emphysematous changes in lungs. Here we report that nSMase2 deficit impairs lung development in mice. We have shown previously that fragilitas ossium (fro) mice carry...
Bewaard in:
| Hoofdauteurs: | , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2012
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4046642/ https://ncbi.nlm.nih.gov/pubmed/22945695 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00335-012-9419-x |
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