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Breast cancer and metabolic syndrome linked through the plasminogen activator inhibitor-1 cycle
Plasminogen activator inhibitor-1 (PAI-1) is a physiological inhibitor of urokinase (uPA), a serine protease known to promote cell migration and invasion. Intuitively, increased levels of PAI-1 should be beneficial in down-regulating uPA activity, particularly in cancer. By contrast, in vivo, increa...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4046619/ https://ncbi.nlm.nih.gov/pubmed/17876797 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.20640 |
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