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Non-coordinate expression of J-chain and Blimp-1 define nurse shark plasma cell populations during ontogeny
Blimp-1 is the master regulator of plasma cell development, controlling genes such as J-chain and secretory Ig heavy chain. However, some mammalian plasma cells do not express J-chain, and mammalian B1 cells secrete “natural” IgM antibodies without upregulating Blimp-1. While these results have been...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4046329/ https://ncbi.nlm.nih.gov/pubmed/23897025 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201343416 |
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