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Putting J-chain back on the map: how might its expression define plasma cell development?()

J-chain (Joining chain) is a small polypeptide that regulates multimerization of secretory IgM and IgA, the only two mammalian Igs capable of forming multimers. J-chain also is required for polyIg-receptor (pIgR)-mediated transport of these Ig classes across the mucosal epithelium. It is generally a...

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Detalhes bibliográficos
Main Authors: Castro, Caitlin D., Flajnik, Martin F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4198949/
https://ncbi.nlm.nih.gov/pubmed/25240020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1400531
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