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Voluntary and forced exercises prevent the development of tolerance to analgesic effects of morphine in rats

OBJECTIVE(S): Morphine is widely used to treat chronic pain. However, its utility is hindered by the development of tolerance to its analgesic effects. Despite the renowned beneficial effects of physical exercise on cognitive functions and signs of morphine withdrawal in morphine-dependent rats, lit...

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Autors principals: Shokraviyan, Monireh, Miladi-Gorji, Hossein, Vaezi, Gholam Hassan
Format: Artigo
Idioma:Inglês
Publicat: Mashhad University of Medical Sciences 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4046236/
https://ncbi.nlm.nih.gov/pubmed/24904720
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