Effect of heat shock protein 70 modulators on the development of morphine analgesic tolerance in rats

The clinical use of opioid analgesics, such as morphine, is limited by analgesic tolerance, molecular mechanism of which is not well understood. Recently, molecular chaperone heat shock protein 70 (Hsp70) has been demonstrated to play important roles in morphine-induced neuroadaptation. Here, we foc...

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Detalhes bibliográficos
Publicado no:Behav Pharmacol
Main Authors: Qin, Wangjun, Zhang, Lei, Tang, Kun, Zhao, Li, Mao, Min, Wang, Yanting, Liang, Jianhui, Zhang, Xianglin, Li, Pengmei
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams and Wilkins 2020
Assuntos:
Research Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7077967/
https://ncbi.nlm.nih.gov/pubmed/31770112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FBP.0000000000000528
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