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The effect of metformin on morphine analgesic tolerance and dependence in rats

Opiate tolerance and dependence is a worldwide public health problem and gives a significant burden to society. The aim of this study was to evaluate the effects of metformin (MET) on development and expression of morphine tolerance and dependence in rats. For induction of tolerance, morphine sulfat...

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Vydáno v:Res Pharm Sci
Hlavní autoři: Fatemi, Iman, Amirteimoury, Morteza, Shamsizadeh, Ali, Kaeidi, Ayat
Médium: Artigo
Jazyk:Inglês
Vydáno: Medknow Publications & Media Pvt Ltd 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6040165/
https://ncbi.nlm.nih.gov/pubmed/30065764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1735-5362.235158
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