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The effect of metformin on morphine analgesic tolerance and dependence in rats

Opiate tolerance and dependence is a worldwide public health problem and gives a significant burden to society. The aim of this study was to evaluate the effects of metformin (MET) on development and expression of morphine tolerance and dependence in rats. For induction of tolerance, morphine sulfat...

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Detalhes bibliográficos
Publicado no:Res Pharm Sci
Main Authors: Fatemi, Iman, Amirteimoury, Morteza, Shamsizadeh, Ali, Kaeidi, Ayat
Formato: Artigo
Idioma:Inglês
Publicado em: Medknow Publications & Media Pvt Ltd 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6040165/
https://ncbi.nlm.nih.gov/pubmed/30065764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1735-5362.235158
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