טוען...
The silent codon change I507-ATC→ATT contributes to the severity of the ΔF508 CFTR channel dysfunction
The most common disease-causing mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene is the out-of-frame deletion of 3 nucleotides (CTT). This mutation leads to the loss of phenylalanine-508 (ΔF508) and a silent codon change (SCC) for isoleucine-507 (I507-ATC→ATT). ΔF508 C...
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| Main Authors: | , , , , , , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Federation of American Societies for Experimental Biology
2013
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4046180/ https://ncbi.nlm.nih.gov/pubmed/23907436 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.13-227330 |
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