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Effect of Cyp27A1 gene dosage on atherosclerosis development in ApoE-knockout mice
In humans, sterol 27-hydroxylase (CYP27A1) deficiency leads to cholesterol deposition in tendons and vasculature. Thus, in addition to its role in bile acid synthesis, where it converts cholesterol to 27-hydroxycholesterol (27-OHC), CYP27A1 may also be atheroprotective. Cyp27A1-deficient (Cyp27A1(−/...
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| Autors principals: | , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Federation of American Societies for Experimental Biology
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4046167/ https://ncbi.nlm.nih.gov/pubmed/24327605 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.13-233791 |
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