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Sterol 27-hydroxylase gene dosage and the antiatherosclerotic effect of Rifampicin in mice

Sterol 27-hydroxylase (CYP27A1) catalyzes the hydroxylation of cholesterol to 27-hydroxycholesterol (27-OHC) and regulates cholesterol homeostasis. In Cyp27a1/ Apolipoprotein E (ApoE) double knockout (KO) mice fed with Western diet (WD), the atherosclerotic phenotype found in ApoE KO mice was revers...

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Detalhes bibliográficos
Publicado no:Biosci Rep
Main Authors: Zurkinden, Line, Sviridov, Dmitri, Vogt, Bruno, Escher, Geneviève
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5784176/
https://ncbi.nlm.nih.gov/pubmed/29191818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20171162
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