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Direct Observation of the Three Regions in α-Synuclein that Determine its Membrane-Bound Behaviour
α-synuclein (αS) is a protein involved in neurotransmitter release in presynaptic terminals, and whose aberrant aggregation is associated with Parkinson’s disease. In dopaminergic neurons, αS exists in a tightly regulated equilibrium between water-soluble and membrane-associated forms. Here we used...
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| Autores principales: | , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4046108/ https://ncbi.nlm.nih.gov/pubmed/24871041 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms4827 |
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