Synthesis, Antimalarial, Antileishmanial, Antimicrobial, Cytotoxicity and Methemoglobin (MetHb) Formation Activities of New 8-Quinolinamines

We report the synthesis, in vitro antiprotozoal (against Plasmodium and Leishmania), antimicrobial, cytotoxicity (Vero and MetHb-producing properties) and in vivo antimalarial activities of two series of 8-quinolinamines. N1-{4-[2-(tert-Butyl)-6-methoxy-8-quinolylamino]pentyl}-(2S/2R)-2-aminosubstit...

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Main Authors: Kaur, Kirandeep, Patel, Sanjay R., Patil, Premanand, Jain, Meenakshi, Khan, Shabana I., Jacob, Melissa R., Tekwani, Babu L., Jain, Rahul
Format: Artigo
Jezik:Inglês
Izdano: 2006
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4045844/
https://ncbi.nlm.nih.gov/pubmed/17084633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2006.10.036
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