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Synthesis, Antiprotozoal, Antimicrobial, β-Hematin Inhibition, Cytotoxicity and Methemoglobin (MetHb) Formation Activities of Bis(8-aminoquinolines)
In continuing our search of potent antimalarials based on 8-aminoquinoline structural framework, three series of novel bis(8-aminoquinolines) using convenient one to four steps synthetic procedures were synthesized. The bisquinolines were evaluated for in vitro antimalarial (P. falciparum), antileis...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3057096/ https://ncbi.nlm.nih.gov/pubmed/21172735 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2010.11.036 |
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