Vaccination with Recombinant Whole Heavy Chain Fragments of Clostridium botulinum Type C and D Neurotoxins

Mice and ducks were subcutaneously immunized with recombinant whole heavy (H) chains of Clostridium botulinum type C and D neurotoxins, which were expressed as glutathione S-transferase fusion proteins. In the case of mice, it was confirmed that two immunizations with type C- and D-H chains, 10 μg e...

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Detalhes bibliográficos
Main Authors: Arimitsu, Hideyuki, Lee, Jae-Chul, Sakaguchi, Yoshihiko, Hayakawa, Yuji, Hayashi, Michiko, Nakaura, Miki, Takai, Hikaru, Lin, Song-Nan, Mukamoto, Masafumi, Murphy, Tom, Oguma, Keiji
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Microbial Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC404583/
https://ncbi.nlm.nih.gov/pubmed/15138174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CDLI.11.3.496-502.2004
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