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Immunological characterization of papain-induced fragments of Clostridium botulinum type A neurotoxin and interaction of the fragments with brain synaptosomes.

After treatment of Clostridium botulinum type A neurotoxin with papain, three fragments (Mrs, 101,000, 45,000, and 43,000) were purified by hydrophobic and ion-exchange chromatography with a high-performance liquid chromatographic system. Immunoblotting analyses with monoclonal antibodies showed tha...

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Detalhes bibliográficos
Publicado no:Infect Immun
Principais autores: Kozaki, S, Miki, A, Kamata, Y, Ogasawara, J, Sakaguchi, G
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC313505/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2668181/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.57.9.2634-2639.1989
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