Immunological characterization of papain-induced fragments of Clostridium botulinum type A neurotoxin and interaction of the fragments with brain synaptosomes.

After treatment of Clostridium botulinum type A neurotoxin with papain, three fragments (Mrs, 101,000, 45,000, and 43,000) were purified by hydrophobic and ion-exchange chromatography with a high-performance liquid chromatographic system. Immunoblotting analyses with monoclonal antibodies showed tha...

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Autores principales: Kozaki, S, Miki, A, Kamata, Y, Ogasawara, J, Sakaguchi, G
Formato: Artigo
Lenguaje:Inglês
Publicado: 1989
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC313505/
https://ncbi.nlm.nih.gov/pubmed/2668181
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