Excess congenital non-synonymous variation in leukemia-associated genes in MLL− infant leukemia: a Children's Oncology Group report

Infant leukemia (IL) is a rare sporadic cancer with a grim prognosis. Although most cases are accompanied by MLL rearrangements and harbor very few somatic mutations, less is known about the genetics of the cases without MLL translocations. We performed the largest exome-sequencing study to date on...

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Detalhes bibliográficos
Main Authors: Valentine, M C, Linabery, A M, Chasnoff, S, Hughes, A E O, Mallaney, C, Sanchez, N, Giacalone, J, Heerema, N A, Hilden, J M, Spector, L G, Ross, J A, Druley, T E
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4045651/
https://ncbi.nlm.nih.gov/pubmed/24301523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2013.367
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