Excess congenital non-synonymous variation in leukemia-associated genes in MLL− infant leukemia: a Children's Oncology Group report

Infant leukemia (IL) is a rare sporadic cancer with a grim prognosis. Although most cases are accompanied by MLL rearrangements and harbor very few somatic mutations, less is known about the genetics of the cases without MLL translocations. We performed the largest exome-sequencing study to date on...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Valentine, M C, Linabery, A M, Chasnoff, S, Hughes, A E O, Mallaney, C, Sanchez, N, Giacalone, J, Heerema, N A, Hilden, J M, Spector, L G, Ross, J A, Druley, T E
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2014
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4045651/
https://ncbi.nlm.nih.gov/pubmed/24301523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2013.367
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky