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Genetic Variants Modify Susceptibility to Leukemia in Infants: A Children’s Oncology Group Report

BACKGROUND: The mixed lineage leukemia (MLL) gene is commonly rearranged in infant leukemia (IL). Genetic determinants of susceptibility to IL are unknown. Recent genome wide association studies for childhood acute lymphoblastic leukemia (ALL) have identified susceptibility loci at IKZF1, ARID5B, an...

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Detalhes bibliográficos
Main Authors: Ross, Julie A., Linabery, Amy M., Blommer, Crystal N., Langer, Erica K., Spector, Logan G., Hilden, Joanne M., Heerema, Nyla A., Radloff, Gretchen A., Tower, Richard L., Davies, Stella M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3381932/
https://ncbi.nlm.nih.gov/pubmed/22422485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.24131
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