Crystal structure of human junctional adhesion molecule 1: Implications for reovirus binding

Reovirus attachment to cells is mediated by the binding of viral attachment protein σ1 to junctional adhesion molecule 1 (JAM1). The crystal structure of the extracellular region of human JAM1 (hJAM1) reveals two concatenated Ig-type domains with a pronounced bend at the domain interface. Two hJAM1...

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Autors principals: Prota, Andrea E., Campbell, Jacquelyn A., Schelling, Pierre, Forrest, J. Craig, Watson, Melissa J., Peters, Timothy R., Aurrand-Lions, Michel, Imhof, Beat A., Dermody, Terence S., Stehle, Thilo
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2003
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC404559/
https://ncbi.nlm.nih.gov/pubmed/12697893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0937718100
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