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Design and application of implicit solvent models in biomolecular simulations

We review implicit solvent models and their parametrisation by introducing the concepts and recent devlopments of the most popular models with a focus on parametrisation via force matching. An overview of recent applications of the solvation energy term in protein dynamics, modelling, design and pre...

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Detalhes bibliográficos
Main Authors: Kleinjung, Jens, Fraternali, Franca
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4045398/
https://ncbi.nlm.nih.gov/pubmed/24841242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2014.04.003
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