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Implicit Solvation Parameters Derived from Explicit Water Forces in Large-Scale Molecular Dynamics Simulations

Implicit solvation is a mean force approach to model solvent forces acting on a solute molecule. It is frequently used in molecular simulations to reduce the computational cost of solvent treatment. In the first instance, the free energy of solvation and the associated solvent–solute forces can be a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kleinjung, Jens, Scott, Walter R. P., Allison, Jane R., van Gunsteren, Wilfred F., Fraternali, Franca
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2012
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3503459/
https://ncbi.nlm.nih.gov/pubmed/23180979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ct200390j
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