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Design and application of implicit solvent models in biomolecular simulations

We review implicit solvent models and their parametrisation by introducing the concepts and recent devlopments of the most popular models with a focus on parametrisation via force matching. An overview of recent applications of the solvation energy term in protein dynamics, modelling, design and pre...

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Dettagli Bibliografici
Autori principali: Kleinjung, Jens, Fraternali, Franca
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier Science 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4045398/
https://ncbi.nlm.nih.gov/pubmed/24841242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2014.04.003
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