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Structural studies of the spliceosome: zooming into the heart of the machine()
Spliceosomes are large, dynamic ribonucleoprotein complexes that catalyse the removal of introns from messenger RNA precursors via a two-step splicing reaction. The recent crystal structure of Prp8 has revealed Reverse Transcriptase-like, Linker and Endonuclease-like domains. The intron branch-point...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Elsevier Science
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4045393/ https://ncbi.nlm.nih.gov/pubmed/24480332 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2013.12.002 |
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