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SHetA2 interference with mortalin binding to p66shc and p53 identified using drug-conjugated magnetic microspheres
SHetA2 is a small molecule flexible heteroarotinoid (Flex-Het) with promising cancer prevention and therapeutic activity. Extensive preclinical testing documented lack of SHetA2 toxicity at doses 25 to 150 fold above effective doses. Knowledge of the SHetA2 molecular target(s) that mediate(s) the me...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer US
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4045313/ https://ncbi.nlm.nih.gov/pubmed/24254390 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10637-013-0041-x |
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