Single-Cell Trajectory Detection Uncovers Progression and Regulatory Coordination in Human B cell Development

Tissue regeneration is an orchestrated progression of cells from an immature state to a mature one, conventionally represented as distinctive cell subsets. A continuum of transitional cell states exists between these discrete stages. We combine the depth of single-cell mass cytometry and an algorith...

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Main Authors: Bendall, Sean C, Davis, Kara L, Amir, El-ad David, Tadmor, Michelle D, Simonds, Erin F, Chen, Tiffany J, Shenfeld, Daniel K, Nolan, Garry P, Pe'er, Dana
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4045247/
https://ncbi.nlm.nih.gov/pubmed/24766814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.04.005
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