Data-driven phenotypic dissection of AML reveals progenitor-like cells that correlate with prognosis

Acute myeloid leukemia (AML) manifests as phenotypically and functionally diverse cells, often within the same patient. Intratumor phenotypic and functional heterogeneity have been linked primarily by physical sorting experiments, which assume that functionally distinct subpopulations can be prospec...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Levine, Jacob H., Simonds, Erin F., Bendall, Sean C., Davis, Kara L., Amir, El-ad D., Tadmor, Michelle, Litvin, Oren, Fienberg, Harris, Jager, Astraea, Zunder, Eli, Finck, Rachel, Gedman, Amanda L., Radtke, Ina, Downing, James R., Pe’er, Dana, Nolan, Garry P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4508757/
https://ncbi.nlm.nih.gov/pubmed/26095251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.05.047
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