Exposure to excess insulin (glargine) induces type 2 diabetes mellitus in mice fed on a chow diet

We have previously shown that insulin plays an important role in the nutrient-induced insulin resistance. In this study, we tested the hypothesis that chronic exposure to excess long-acting insulin (glargine) can cause typical type 2 diabetes mellitus (T2DM) in normal mice fed on a chow diet. C57BL/...

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Main Authors: Yang, Xuefeng, Mei, Shuang, Gu, Haihua, Guo, Huailan, Zha, Longying, Cai, Junwei, Li, Xuefeng, Liu, Zhenqi, Cao, Wenhong
Formato: Artigo
Idioma:Inglês
Publicado em: Bioscientifica Ltd 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4045231/
https://ncbi.nlm.nih.gov/pubmed/24741073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JOE-14-0117
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