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Insulin and insulin signaling play a critical role in fat induction of insulin resistance in mouse

The primary player that induces insulin resistance has not been established. Here, we studied whether or not fat can cause insulin resistance in the presence of insulin deficiency. Our results showed that high-fat diet (HFD) induced insulin resistance in C57BL/6 (B6) mice. The HFD-induced insulin re...

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Главные авторы: Ning, Jie, Hong, Tao, Yang, Xuefeng, Mei, Shuang, Liu, Zhenqi, Liu, Hui-Yu, Cao, Wenhong
Формат: Artigo
Язык:Inglês
Опубликовано: American Physiological Society 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3154527/
https://ncbi.nlm.nih.gov/pubmed/21586696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00164.2011
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