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p38 Mitogen-activated Protein Kinase (MAPK) Promotes Cholesterol Ester Accumulation in Macrophages through Inhibition of Macroautophagy

p38 MAPK has been strongly implicated in the development of atherosclerosis, but its role in cholesterol ester accumulation in macrophages and formation of foam cells, an early step in the development of atherosclerosis, has not been investigated. We addressed this issue and made some brand new obse...

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Detalhes bibliográficos
Main Authors: Mei, Shuang, Gu, Haihua, Ward, Adam, Yang, Xuefeng, Guo, Huailan, He, Ka, Liu, Zhenqi, Cao, Wenhong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3320924/
https://ncbi.nlm.nih.gov/pubmed/22354961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.333575
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