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Enhanced Specialized Transduction Using Recombineering in Mycobacterium tuberculosis

Genetic engineering has contributed greatly to our understanding of Mycobacterium tuberculosis biology and has facilitated antimycobacterial and vaccine development. However, methods to generate M. tuberculosis deletion mutants remain labor-intensive and relatively inefficient. Here, methods are des...

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Détails bibliographiques
Auteurs principaux: Tufariello, JoAnn M., Malek, Adel A., Vilchèze, Catherine, Cole, Laura E., Ratner, Hannah K., González, Pablo A., Jain, Paras, Hatfull, Graham F., Larsen, Michelle H., Jacobs, William R.
Format: Artigo
Langue:Inglês
Publié: American Society of Microbiology 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4045075/
https://ncbi.nlm.nih.gov/pubmed/24865558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01179-14
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