Enhanced Specialized Transduction Using Recombineering in Mycobacterium tuberculosis

Genetic engineering has contributed greatly to our understanding of Mycobacterium tuberculosis biology and has facilitated antimycobacterial and vaccine development. However, methods to generate M. tuberculosis deletion mutants remain labor-intensive and relatively inefficient. Here, methods are des...

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Detalhes bibliográficos
Main Authors: Tufariello, JoAnn M., Malek, Adel A., Vilchèze, Catherine, Cole, Laura E., Ratner, Hannah K., González, Pablo A., Jain, Paras, Hatfull, Graham F., Larsen, Michelle H., Jacobs, William R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Microbiology 2014
Assuntos:
Observation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4045075/
https://ncbi.nlm.nih.gov/pubmed/24865558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01179-14
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