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Allospecific rejection of MHC class I-deficient bone marrow by CD8 T cells

Avoidance of long-term immunosuppression is a desired goal in organ transplantation. Mixed chimerism offers a promising approach to tolerance induction, and we have aimed to develop low-toxicity, non-immunodepleting approaches to achieve this outcome. In a mouse model achieving fully MHC-mismatched...

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Hlavní autoři: Haspot, Fabienne, Li, Hao Wei, Lucas, Carrie L., Fehr, Thomas, Beyaz, Semir, Sykes, Megan
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4045013/
https://ncbi.nlm.nih.gov/pubmed/24304495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.12525
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