Silencing of KIF14 interferes with cell cycle progression and cytokinesis by blocking the p27(Kip1) ubiquitination pathway in hepatocellular carcinoma

Although it has been suggested that kinesin family member 14 (KIF14) has oncogenic potential in various cancers, including hepatocellular carcinoma (HCC), the molecular mechanism of this potential remains unknown. We aimed to elucidate the role of KIF14 in hepatocarcinogenesis by knocking down KIF14...

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Autores principales: Xu, Haidong, Choe, Chungyoul, Shin, Seung-Hun, Park, Sung-Won, Kim, Ho-Shik, Jung, Seung-Hyun, Yim, Seon-Hee, Kim, Tae-Min, Chung, Yeun-Jun
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2014
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4044675/
https://ncbi.nlm.nih.gov/pubmed/24854087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2014.23
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