In Vivo Synthesis of Mammalian-Like, Hybrid-Type N-Glycans in Pichia pastoris
The Pichia pastoris N-glycosylation pathway is only partially homologous to the pathway in human cells. In the Golgi apparatus, human cells synthesize complex oligosaccharides, whereas Pichia cells form mannose structures that can contain up to 40 mannose residues. This hypermannosylation of secrete...
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| Publié dans: | Appl Environ Microbiol |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology (ASM)
2004
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC404441/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15128513/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AEM.70.5.2639-2646.2004 |
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