In Vivo Synthesis of Mammalian-Like, Hybrid-Type N-Glycans in Pichia pastoris

The Pichia pastoris N-glycosylation pathway is only partially homologous to the pathway in human cells. In the Golgi apparatus, human cells synthesize complex oligosaccharides, whereas Pichia cells form mannose structures that can contain up to 40 mannose residues. This hypermannosylation of secrete...

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書目詳細資料

發表在:	Appl Environ Microbiol
Principais autores:	Vervecken, Wouter, Kaigorodov, Vladimir, Callewaert, Nico, Geysens, Steven, De Vusser, Kristof, Contreras, Roland
格式:	Artigo
語言:	Inglês
出版:	American Society for Microbiology (ASM) 2004
主題:	Physiology and Biotechnology
在線閱讀:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC404441/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15128513/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AEM.70.5.2639-2646.2004
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