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FUS is Phosphorylated by DNA-PK and Accumulates in the Cytoplasm after DNA Damage

Abnormal cytoplasmic accumulation of Fused in Sarcoma (FUS) in neurons defines subtypes of amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD). FUS is a member of the FET protein family that includes Ewing's sarcoma (EWS) and TATA-binding protein-associated factor 2...

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Detalhes bibliográficos
Main Authors: Deng, Qiudong, Holler, Christopher J., Taylor, Georgia, Hudson, Kathryn F., Watkins, William, Gearing, Marla, Ito, Daisuke, Murray, Melissa E., Dickson, Dennis W., Seyfried, Nicholas T., Kukar, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4044245/
https://ncbi.nlm.nih.gov/pubmed/24899704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0172-14.2014
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